![(E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide structure](/static/products/620/620109-78-6.png)
(E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide
TL;DR: (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide (CAS 620109-78-6) is a chemical compound with molecular formula C18H10Cl2N4O3 and molecular weight 400.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-3-[2-(2,4-dichlorophenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide
Also Known As: (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide, (E)-2-cyano-3-[2-(2,4-dichlorophenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide, (2E)-2-cyano-3-[2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide
| Molecular Formula | C18H10Cl2N4O3 |
|---|---|
| Molecular Weight | 400.01 g/mol |
| LogP | 3.18588 |
| Topological Polar Surface Area | 110.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 400.013 |
| Heavy Atoms | 27 |
| Complexity | 1195.4115 |
Chemical Identifiers
| CAS Number | 620109-78-6 |
|---|---|
| SMILES | C1=CC2=NC(=C(C(=O)N2C=C1)/C=C(\C#N)/C(=O)N)OC3=C(C=C(C=C3)Cl)Cl |
Product Overview
(E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide (CAS 620109-78-6), with molecular formula C18H10Cl2N4O3 and molecular weight 400.01 g/mol. IUPAC: (E)-2-cyano-3-[2-(2,4-dichlorophenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide.
Chemical Property Profile of (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide
Property Insights of (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide
The XLogP value of 3.18588 indicates that (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.48 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide. Following Lipinski's Rule of Five, (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide?
The CAS number of (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide is 620109-78-6.
What is the molecular formula of (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide?
The molecular formula of (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide is C18H10Cl2N4O3.
What is the molecular weight of (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide?
The molecular weight of (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide is 400.01 g/mol.
Where can I buy (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide?
You can request a quote for (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-cyano-3-(2-(2,4-dichlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.