4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile
TL;DR: 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile (CAS 133707-66-1) is a chemical compound with molecular formula C18H10Cl2N2O and molecular weight 340.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4,6-bis(4-chlorophenyl)-2-oxo-1H-pyridine-3-carbonitrile
Also Known As: 4,6-bis(4-chlorophenyl)-2-hydroxynicotinonitrile, 9L-591S, 4,6-bis(4-chlorophenyl)-2-oxo-1H-pyridine-3-carbonitrile, J3.139.789H, 4,6-bis(4-chlorophenyl)-2-hydroxypyridine-3-carbonitrile
| Molecular Formula | C18H10Cl2N2O |
|---|---|
| Molecular Weight | 340.02 g/mol |
| LogP | 4.88738 |
| Topological Polar Surface Area | 56.65 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 340.01703 |
| Heavy Atoms | 23 |
| Complexity | 952.2971 |
Chemical Identifiers
| CAS Number | 133707-66-1 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=CC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl)Cl |
Product Overview
4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile (CAS 133707-66-1), with molecular formula C18H10Cl2N2O and molecular weight 340.02 g/mol. IUPAC: 4,6-bis(4-chlorophenyl)-2-oxo-1H-pyridine-3-carbonitrile.
Chemical Property Profile of 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile
Property Insights of 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile
The XLogP value of 4.88738 indicates that 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.65 Ų, 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile?
The CAS number of 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile is 133707-66-1.
What is the molecular formula of 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile?
The molecular formula of 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile is C18H10Cl2N2O.
What is the molecular weight of 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile?
The molecular weight of 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile is 340.02 g/mol.
Where can I buy 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile?
You can request a quote for 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile?
Yes, KEHONG BIO provides custom synthesis services for 4,6-Bis(4-chlorophenyl)-2-hydroxynicotinonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.