Bleomycin A1 structure

Bleomycin A1

TL;DR: Bleomycin A1 (CAS 58995-26-9) is a chemical compound with molecular formula C54H81N17O22S3 and molecular weight 1415.49 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[3-hydroxy-5-[[3-hydroxy-1-[2-[4-[4-(3-methylsulfinylpropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate

Also Known As: Bleomycin A1, N1-(3-(Methylsulfinyl)propyl)bleomycinamide, Bleomycinamide, N(sup 1)-(3-(methylsulfinyl)propyl)-, 2-({2-[2-{[(6-amino-2-{3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl}-5-methylpyrimidin-4-yl)carbonyl]amino}-3-({3-hydroxy-5-[(3-hydroxy-1-{[2-(4-{[3-(methylsulfinyl)propyl]carbamoyl}-2,4'-bi-1,3-thiazol-2'-yl)ethyl]amino}-1-oxobutan-2-yl)amino]-4-methyl-5-oxopentan-2-yl}amino)-1-(1h-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-3-yl}oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-4-yl carbamate(non-preferred name), [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[3-hydroxy-5-[[3-hydroxy-1-[2-[4-[4-(3-methylsulfinylpropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate

CAS: 58995-26-9
Molecular Formula C54H81N17O22S3
Molecular Weight 1415.49 g/mol
LogP -9.1
Topological Polar Surface Area 720.0 Ų
Hydrogen Bond Donors 20
Hydrogen Bond Acceptors 33
Rotatable Bonds 36
Exact Mass 1415.4905
Heavy Atoms 96
Complexity 2630.0

Chemical Identifiers

CAS Number 58995-26-9
SMILES CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCS(=O)C)O
InChIKey GMYNGXLEGQPRFK-UHFFFAOYSA-N

Product Overview

Bleomycin A1 (CAS 58995-26-9), with molecular formula C54H81N17O22S3 and molecular weight 1415.49 g/mol. IUPAC: [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[3-hydroxy-5-[[3-hydroxy-1-[2-[4-[4-(3-methylsulfinylpropylcarbamoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Bleomycin A1

XLogP
-9.1
TPSA (Topological Polar Surface Area)
720.0
Hydrogen Bond Donors
20
Hydrogen Bond Acceptors
33
Rotatable Bonds
36
Heavy Atoms
96
Complexity
2630.0
Exact Mass
1415.4905
Monoisotopic Mass
1415.4905
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Bleomycin A1

The XLogP value of -9.1 indicates that Bleomycin A1 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 720.0 Ų indicates high polarity, suggesting Bleomycin A1 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bleomycin A1 has 20 hydrogen bond donor(s) and 33 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Bleomycin A1?

The CAS number of Bleomycin A1 is 58995-26-9.

What is the molecular formula of Bleomycin A1?

The molecular formula of Bleomycin A1 is C54H81N17O22S3.

What is the molecular weight of Bleomycin A1?

The molecular weight of Bleomycin A1 is 1415.49 g/mol.

Where can I buy Bleomycin A1?

You can request a quote for Bleomycin A1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Bleomycin A1?

Yes, KEHONG BIO provides custom synthesis services for Bleomycin A1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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