![(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮 structure](/static/products/108/108466-41-7.webp)
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮
概要：(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮（CAS 108466-41-7）是一种化学化合物，分子式为C63H113N11O12，分子量为1215.86 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,27,28-decamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
又称：Meala(3)Cs, 8-(N-Methylalanine)cyclosporin A, Cyclosporin A 8-N-MeAla, 8-(N-Methyl-D-alanine)cyclosporin A, 8-(N-Methyl-L-alanine)cyclosporin A
| 分子式 | C63H113N11O12 |
|---|---|
| 分子量 | 1215.86 g/mol |
| LogP | 3.6575 |
| 拓扑极性表面积 | 278.8 Ų |
| 氢键供体数 | 5 |
| 氢键受体数 | 12 |
| 可旋转键数 | 15 |
| 精确质量 | 1215.857 |
| 重原子数 | 86 |
| 复杂度 | 2360.5137 |
化学标识符
| CAS 编号 | 108466-41-7 |
|---|---|
| SMILES | CC[C@H]1C(=O)N([C@@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N(C(C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)C |
📋 应用领域
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮主要应用于有机合成与工艺化学。在实验室中常作为通用有机合成砌块使用。科弘生物可提供该产品的目录供应与定制合成服务（毫克至吨级），配套HPLC/NMR/MS全套检测与COA、MSDS文档。
产品概述
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮（CAS 108466-41-7）属于精细化学品，其分子式为C63H113N11O12，分子量 1215.86 g/mol。 常用别名包括Meala(3)Cs、8-(N-Methylalanine)cyclosporin A。
支持定制合成与批量供应，提供完整的分析检测文档。欢迎提供目标数量与纯度要求，获取实时报价。
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮化学性质概览
属性洞察：(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮的XLogP值为3.6575，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为278.8 Ų，极性较高，提示该化合物膜透过性可能受限但水溶性较好。 根据Lipinski五规则，(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮有5个氢键供体和12个氢键受体，可能需要考虑配方优化。
常见问题
常见问题
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮的CAS号是多少？
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮的CAS号为108466-41-7。
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮的分子式是什么？
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮的分子式为C63H113N11O12。
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮的分子量是多少？
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮的分子量为1215.86 g/mol。
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮有哪些应用？
(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮主要应用于有机合成与工艺化学。在实验室中常作为通用有机合成砌块使用。科弘生物可提供该产品的目录供应与定制合成服务（毫克至吨级），配套HPLC/NMR/MS全套检测与COA、MSDS文档。
在哪里可以购买(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮？
您可以直接向科弘生物询价(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮的定制合成服务？
是的，科弘生物提供(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S)-30-乙基-33-[(E,1R,2R)-1-羟基-2-甲基己-4-烯基]-1,4,7,10,12,15,19,25,27,28-十甲基-6,9,18,24-四(2-甲基丙基)-3,21-二(异丙基)-1,4,7,10,13,16,19,22,25,28,31-十一氮杂环三十烷-2,5,8,11,14,17,20,23,26,29,32-十一酮及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。