Icr 372
TL;DR: Icr 372 (CAS 36167-69-8) is a chemical compound with molecular formula C18H22Cl4N4O and molecular weight 450.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)propane-1,3-diamine;dihydrochloride
Also Known As: Icr 372, 1,3-Propanediamine, N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)-, dihydrochloride, n-(2-chloroethyl)-n'-(7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)-1,3-propanediamine dihydrochloride, N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)propane-1,3-diamine;dihydrochloride, 1-Aza-6-chloro-2-methoxy-9-[[3-[(2-chloroethyl)amino]propyl]amino]acridine dihydrochloride
| Molecular Formula | C18H22Cl4N4O |
|---|---|
| Molecular Weight | 450.05 g/mol |
| LogP | 4.92 |
| Topological Polar Surface Area | 59.1 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 452.05182 |
| Heavy Atoms | 27 |
| Complexity | 403.0 |
Chemical Identifiers
| CAS Number | 36167-69-8 |
|---|---|
| SMILES | COC1=NC2=C(C3=C(C=C(C=C3)Cl)N=C2C=C1)NCCCNCCCl.Cl.Cl |
| InChIKey | LWGQNPCCIGPMNB-UHFFFAOYSA-N |
Product Overview
Icr 372 (CAS 36167-69-8), with molecular formula C18H22Cl4N4O and molecular weight 450.05 g/mol. IUPAC: N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)propane-1,3-diamine;dihydrochloride.
Chemical Property Profile of Icr 372
Property Insights of Icr 372
The XLogP value of 4.92 indicates that Icr 372 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.1 Ų, Icr 372 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Icr 372 has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Icr 372?
The CAS number of Icr 372 is 36167-69-8.
What is the molecular formula of Icr 372?
The molecular formula of Icr 372 is C18H22Cl4N4O.
What is the molecular weight of Icr 372?
The molecular weight of Icr 372 is 450.05 g/mol.
Where can I buy Icr 372?
You can request a quote for Icr 372 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Icr 372?
Yes, KEHONG BIO provides custom synthesis services for Icr 372 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.