L-377202
TL;DR: L-377202 (CAS 207395-85-5) is a chemical compound with molecular formula C65H89N9O25 and molecular weight 1395.60 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[(2S,4R)-2-[[(2S)-1-[[(2S)-1-[[(1S)-2-[[(2S)-5-amino-1-[[(2S)-3-hydroxy-1-[[(2S)-1-[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-cyclohexyl-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]-4-hydroxypyrrolidin-1-yl]-5-oxopentanoic acid
Also Known As: L-377202, Doxorubicin Prodrug L-377,202, L 377202, L-377202-000H, L-377,202
| Molecular Formula | C65H89N9O25 |
|---|---|
| Molecular Weight | 1395.60 g/mol |
| LogP | -3.8193 |
| Topological Polar Surface Area | 545.14 Ų |
| Hydrogen Bond Donors | 17 |
| Hydrogen Bond Acceptors | 24 |
| Rotatable Bonds | 31 |
| Exact Mass | 1395.5969 |
| Heavy Atoms | 99 |
| Complexity | 3433.7883 |
Chemical Identifiers
| CAS Number | 207395-85-5 |
|---|---|
| SMILES | C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](C6CCCCC6)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H]7C[C@H](CN7C(=O)CCCC(=O)O)O)O |
Product Overview
L-377202 (CAS 207395-85-5), with molecular formula C65H89N9O25 and molecular weight 1395.60 g/mol. IUPAC: 5-[(2S,4R)-2-[[(2S)-1-[[(2S)-1-[[(1S)-2-[[(2S)-5-amino-1-[[(2S)-3-hydroxy-1-[[(2S)-1-[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-cyclohexyl-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]-4-hydroxypyrrolidin-1-yl]-5-oxopentanoic acid.
Chemical Property Profile of L-377202
Property Insights of L-377202
The XLogP value of -3.8193 indicates that L-377202 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 545.14 Ų indicates high polarity, suggesting L-377202 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, L-377202 has 17 hydrogen bond donor(s) and 24 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L-377202?
The CAS number of L-377202 is 207395-85-5.
What is the molecular formula of L-377202?
The molecular formula of L-377202 is C65H89N9O25.
What is the molecular weight of L-377202?
The molecular weight of L-377202 is 1395.60 g/mol.
Where can I buy L-377202?
You can request a quote for L-377202 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L-377202?
Yes, KEHONG BIO provides custom synthesis services for L-377202 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.