Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala structure

Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala

TL;DR: Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala (CAS 117592-22-0) is a chemical compound with molecular formula C55H82N14O16 and molecular weight 1194.60 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[[2-[[2-[[1-[2-[2-[[5-amino-2-[[2-[(2-amino-3-hydroxybutanoyl)amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]propanoylamino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(1-carboxyethylamino)-5-oxopentanoic acid

Also Known As: Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala, RETROVIRAL PROTEASE SUBSTRATE, T-F-Q-A-Y-P-L-R-E-A, H-Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala-OH, 4-[[2-[[2-[[1-[2-[2-[[5-amino-2-[[2-[(2-amino-3-hydroxybutanoyl)amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]propanoylamino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(1-carboxyethylamino)-5-oxopentanoic acid

CAS: 117592-22-0
Molecular Formula C55H82N14O16
Molecular Weight 1194.60 g/mol
LogP -3.8907
Topological Polar Surface Area 501.68 Ų
Hydrogen Bond Donors 16
Hydrogen Bond Acceptors 16
Rotatable Bonds 35
Exact Mass 1194.6033
Heavy Atoms 85
Complexity 2691.539

Chemical Identifiers

CAS Number 117592-22-0
SMILES CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)O)NC(=O)C1CCCN1C(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)O)N

Product Overview

Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala (CAS 117592-22-0), with molecular formula C55H82N14O16 and molecular weight 1194.60 g/mol. IUPAC: 4-[[2-[[2-[[1-[2-[2-[[5-amino-2-[[2-[(2-amino-3-hydroxybutanoyl)amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]propanoylamino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(1-carboxyethylamino)-5-oxopentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala

XLogP
-3.8907
TPSA (Topological Polar Surface Area)
501.68
Hydrogen Bond Donors
16
Hydrogen Bond Acceptors
16
Rotatable Bonds
35
Heavy Atoms
85
Complexity
2691.539
Exact Mass
1194.6033
Monoisotopic Mass
1194.6033
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala

The XLogP value of -3.8907 indicates that Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 501.68 Ų indicates high polarity, suggesting Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala has 16 hydrogen bond donor(s) and 16 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala?

The CAS number of Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala is 117592-22-0.

What is the molecular formula of Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala?

The molecular formula of Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala is C55H82N14O16.

What is the molecular weight of Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala?

The molecular weight of Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala is 1194.60 g/mol.

Where can I buy Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala?

You can request a quote for Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala?

Yes, KEHONG BIO provides custom synthesis services for Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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