Sennoside E structure

Sennoside E

TL;DR: Sennoside E (CAS 11137-63-6) is a chemical compound with molecular formula C44H38O23 and molecular weight 934.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

9-[2-carboxy-5-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-oxalooxyoxan-2-yl]oxy-4-hydroxy-10-oxo-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

Also Known As: Sennoside E, Sennoside F, 9-[2-carboxy-5-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-oxalooxyoxan-2-yl]oxy-4-hydroxy-10-oxo-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid, (9,9'-Bianthracene)-2,2'-dicarboxylic acid, 5-((O-(carboxycarbonyl)-beta-D-glucopyranosyl)oxy)-5'-(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (R*,R*)-, 9-[2-carboxy-4-hydroxy-10-oxo-5-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9h-anthracen-9-yl]-5-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-3-oxalooxyoxan-2-yl]oxy-4-hydroxy-10-oxo-9h-anthracene-2-carboxylic acid

CAS: 11137-63-6
Molecular Formula C44H38O23
Molecular Weight 934.18 g/mol
LogP -1.4601
Topological Polar Surface Area 391.33 Ų
Hydrogen Bond Donors 12
Hydrogen Bond Acceptors 20
Rotatable Bonds 10
Exact Mass 934.18036
Heavy Atoms 67
Complexity 2729.8328

Chemical Identifiers

CAS Number 11137-63-6
SMILES C1=CC2=C(C(=C1)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)OC(=O)C(=O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

Product Overview

Sennoside E (CAS 11137-63-6), with molecular formula C44H38O23 and molecular weight 934.18 g/mol. IUPAC: 9-[2-carboxy-5-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-oxalooxyoxan-2-yl]oxy-4-hydroxy-10-oxo-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Sennoside E

XLogP
-1.4601
TPSA (Topological Polar Surface Area)
391.33
Hydrogen Bond Donors
12
Hydrogen Bond Acceptors
20
Rotatable Bonds
10
Heavy Atoms
67
Complexity
2729.8328
Exact Mass
934.18036
Monoisotopic Mass
934.18036
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Sennoside E

The XLogP value of -1.4601 indicates that Sennoside E is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 391.33 Ų indicates high polarity, suggesting Sennoside E may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Sennoside E has 12 hydrogen bond donor(s) and 20 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Sennoside E?

The CAS number of Sennoside E is 11137-63-6.

What is the molecular formula of Sennoside E?

The molecular formula of Sennoside E is C44H38O23.

What is the molecular weight of Sennoside E?

The molecular weight of Sennoside E is 934.18 g/mol.

Where can I buy Sennoside E?

You can request a quote for Sennoside E directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Sennoside E?

Yes, KEHONG BIO provides custom synthesis services for Sennoside E and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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