Endothelin (16-21) structure

Endothelin (16-21)

TL;DR: Endothelin (16-21) (CAS 121377-67-1) is a chemical compound with molecular formula C39H57N9O9 and molecular weight 795.43 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3S)-3-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-[[(2S,3S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid

Also Known As: Endothelin (16-21), His-leu-asp-ile-ile-trp, Endothelin(16-21), H-HLDIIW-OH, Endothelin 1(16-21)

CAS: 121377-67-1
Molecular Formula C39H57N9O9
Molecular Weight 795.43 g/mol
LogP -1.0
Topological Polar Surface Area 291.0 Ų
Hydrogen Bond Donors 10
Hydrogen Bond Acceptors 11
Rotatable Bonds 23
Exact Mass 795.4279
Heavy Atoms 57
Complexity 1400.0

Chemical Identifiers

CAS Number 121377-67-1
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CN=CN3)N
InChIKey NTSBFTNRWQVBCA-IVGDYKFASA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Organic Building Blocks (2 patents) Peptides & Amino Acids (6 patents) Pharmaceutical Intermediates (7 patents)

Product Overview

Endothelin (16-21) (CAS 121377-67-1), with molecular formula C39H57N9O9 and molecular weight 795.43 g/mol. IUPAC: (3S)-3-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-[[(2S,3S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Endothelin (16-21)

XLogP
-1.0
TPSA (Topological Polar Surface Area)
291.0
Hydrogen Bond Donors
10
Hydrogen Bond Acceptors
11
Rotatable Bonds
23
Heavy Atoms
57
Complexity
1400.0
Exact Mass
795.4279
Monoisotopic Mass
795.4279
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Endothelin (16-21)

The XLogP value of -1.0 indicates that Endothelin (16-21) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 291.0 Ų indicates high polarity, suggesting Endothelin (16-21) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Endothelin (16-21) has 10 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Endothelin (16-21)?

The CAS number of Endothelin (16-21) is 121377-67-1.

What is the molecular formula of Endothelin (16-21)?

The molecular formula of Endothelin (16-21) is C39H57N9O9.

What is the molecular weight of Endothelin (16-21)?

The molecular weight of Endothelin (16-21) is 795.43 g/mol.

Where can I buy Endothelin (16-21)?

You can request a quote for Endothelin (16-21) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Endothelin (16-21)?

Yes, KEHONG BIO provides custom synthesis services for Endothelin (16-21) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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