K-252b
TL;DR: K-252b (CAS 99570-78-2) is a chemical compound with molecular formula C26H19N3O5 and molecular weight 453.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
K-252b
16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylic acid
Also Known As: k-252b, Staurosporine aglycone, K252b, K-252b,, (15S,16R,18R)-16-Hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylic acid
| Molecular Formula | C26H19N3O5 |
|---|---|
| Molecular Weight | 453.13 g/mol |
| LogP | 2.4 |
| Topological Polar Surface Area | 106.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 453.13248 |
| Heavy Atoms | 34 |
| Complexity | 961.0 |
Chemical Identifiers
| CAS Number | 99570-78-2 |
|---|---|
| SMILES | CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O |
| InChIKey | AMSOPBXQXSAAAC-UHFFFAOYSA-N |
Product Overview
K-252b (CAS 99570-78-2), with molecular formula C26H19N3O5 and molecular weight 453.13 g/mol. IUPAC: 16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylic acid.
Chemical Property Profile of K-252b
Property Insights of K-252b
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for K-252b. The TPSA of 106.0 Ų falls within the moderate polarity range, balancing permeability and solubility for K-252b. Following Lipinski's Rule of Five, k-252b has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of k-252b?
The CAS number of k-252b is 99570-78-2.
What is the molecular formula of k-252b?
The molecular formula of k-252b is C26H19N3O5.
What is the molecular weight of k-252b?
The molecular weight of k-252b is 453.13 g/mol.
Where can I buy k-252b?
You can request a quote for k-252b directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for k-252b?
Yes, KEHONG BIO provides custom synthesis services for k-252b and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.