K-252a
TL;DR: K-252a (CAS 97161-97-2) is a chemical compound with molecular formula C27H21N3O5 and molecular weight 467.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
K-252a
methyl 16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate
Also Known As: k-252a, staurosporinone, Antibiotic K 252a, Staurosporine aglycone, K252a
| Molecular Formula | C27H21N3O5 |
|---|---|
| Molecular Weight | 467.15 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 94.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 467.14813 |
| Heavy Atoms | 35 |
| Complexity | 976.0 |
Chemical Identifiers
| CAS Number | 97161-97-2 |
|---|---|
| SMILES | CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O |
| InChIKey | KOZFSFOOLUUIGY-UHFFFAOYSA-N |
Product Overview
K-252a (CAS 97161-97-2), with molecular formula C27H21N3O5 and molecular weight 467.15 g/mol. IUPAC: methyl 16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate.
Chemical Property Profile of K-252a
Property Insights of K-252a
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for K-252a. The TPSA of 94.7 Ų falls within the moderate polarity range, balancing permeability and solubility for K-252a. Following Lipinski's Rule of Five, k-252a has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of k-252a?
The CAS number of k-252a is 97161-97-2.
What is the molecular formula of k-252a?
The molecular formula of k-252a is C27H21N3O5.
What is the molecular weight of k-252a?
The molecular weight of k-252a is 467.15 g/mol.
Where can I buy k-252a?
You can request a quote for k-252a directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for k-252a?
Yes, KEHONG BIO provides custom synthesis services for k-252a and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.