氨氯地平
TL;DR: 氨氯地平 (CAS 88150-42-9) is a chemical compound with molecular formula C20H25ClN2O5 and molecular weight 408.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氨氯地平
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: amlodipine, Norvasc, Amlodipino, Amlodipinum, Amlocard
| Molecular Formula | C20H25ClN2O5 |
|---|---|
| Molecular Weight | 408.15 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 99.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 10 |
| Exact Mass | 408.1452 |
| Heavy Atoms | 28 |
| Complexity | 647.0 |
| Melting Point | 199-201 |
| Boiling Point | 527.2 |
| Solubility | slightly soluble in water |
Chemical Identifiers
| CAS Number | 88150-42-9 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN |
| InChIKey | HTIQEAQVCYTUBX-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 15 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
氨氯地平 (CAS 88150-42-9), with molecular formula C20H25ClN2O5 and molecular weight 408.15 g/mol. IUPAC: 3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of 氨氯地平
Property Insights of 氨氯地平
The XLogP value of 3.0 indicates that 氨氯地平 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 氨氯地平. Following Lipinski's Rule of Five, 氨氯地平 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 氨氯地平?
The CAS number of 氨氯地平 is 88150-42-9.
What is the molecular formula of 氨氯地平?
The molecular formula of 氨氯地平 is C20H25ClN2O5.
What is the molecular weight of 氨氯地平?
The molecular weight of 氨氯地平 is 408.15 g/mol.
Where can I buy 氨氯地平?
You can request a quote for 氨氯地平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 氨氯地平?
Yes, KEHONG BIO provides custom synthesis services for 氨氯地平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.