1-(5-异喹啉磺酰基)-2-甲基哌嗪 structure

1-(5-异喹啉磺酰基)-2-甲基哌嗪

TL;DR: 1-(5-异喹啉磺酰基)-2-甲基哌嗪 (CAS 84477-87-2) is a chemical compound with molecular formula C14H17N3O2S and molecular weight 291.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(5-异喹啉磺酰基)-2-甲基哌嗪

5-(2-methylpiperazin-1-yl)sulfonylisoquinoline

Also Known As: Protein kinase inhibitor H-7, Isoquinoline deriv., H-7 dihydrochloride, H-7 inhibitor, 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE

CAS: 84477-87-2
Molecular Formula C14H17N3O2S
Molecular Weight 291.10 g/mol
LogP 1.0
Topological Polar Surface Area 70.7 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 291.10416
Heavy Atoms 20
Complexity 434.0

Chemical Identifiers

CAS Number 84477-87-2
SMILES CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3
InChIKey BDVFVCGFMNCYPV-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (21 patents) Analytical Reagents (49 patents) Biotechnology (257 patents) Heterocyclic Building Blocks (115 patents) Organic Building Blocks (22 patents) +2 more

Product Overview

1-(5-异喹啉磺酰基)-2-甲基哌嗪 (CAS 84477-87-2), with molecular formula C14H17N3O2S and molecular weight 291.10 g/mol. IUPAC: 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1-(5-异喹啉磺酰基)-2-甲基哌嗪

XLogP
1.0
TPSA (Topological Polar Surface Area)
70.7
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
20
Complexity
434.0
Exact Mass
291.10416
Monoisotopic Mass
291.10416
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(5-异喹啉磺酰基)-2-甲基哌嗪

The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(5-异喹啉磺酰基)-2-甲基哌嗪. The TPSA of 70.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(5-异喹啉磺酰基)-2-甲基哌嗪. Following Lipinski's Rule of Five, 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?

The CAS number of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine is 84477-87-2.

What is the molecular formula of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?

The molecular formula of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine is C14H17N3O2S.

What is the molecular weight of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?

The molecular weight of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine is 291.10 g/mol.

Where can I buy 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?

You can request a quote for 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?

Yes, KEHONG BIO provides custom synthesis services for 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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