Thiopropazate
TL;DR: Thiopropazate (CAS 84-06-0) is a chemical compound with molecular formula C23H28ClN3O2S and molecular weight 445.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethyl acetate
Also Known As: THIOPROPAZATE, Thiopropazat, Dartalan, Tiopropazato, Dartal
| Molecular Formula | C23H28ClN3O2S |
|---|---|
| Molecular Weight | 445.16 g/mol |
| LogP | 4.8 |
| Topological Polar Surface Area | 61.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 445.1591 |
| Heavy Atoms | 30 |
| Complexity | 561.0 |
| Melting Point | MP: 167-169 °C /DIMALEATE/ |
| Boiling Point | 214-218 °C @ 0.1 MM HG |
| Solubility | SOL IN ETHER |
| Refractive Index | 1.589 (ALPHA), 1.609 (BETA), 1.700 (GAMMA) /DIHYDROCHLORIDE/ |
Chemical Identifiers
| CAS Number | 84-06-0 |
|---|---|
| SMILES | CC(=O)OCCN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl |
| InChIKey | AIUHRQHVWSUTGJ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Thiopropazate (CAS 84-06-0), with molecular formula C23H28ClN3O2S and molecular weight 445.16 g/mol. IUPAC: 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethyl acetate.
Chemical Property Profile of Thiopropazate
Property Insights of Thiopropazate
The XLogP value of 4.8 indicates that Thiopropazate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Thiopropazate. Following Lipinski's Rule of Five, Thiopropazate has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thiopropazate?
The CAS number of Thiopropazate is 84-06-0.
What is the molecular formula of Thiopropazate?
The molecular formula of Thiopropazate is C23H28ClN3O2S.
What is the molecular weight of Thiopropazate?
The molecular weight of Thiopropazate is 445.16 g/mol.
Where can I buy Thiopropazate?
You can request a quote for Thiopropazate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thiopropazate?
Yes, KEHONG BIO provides custom synthesis services for Thiopropazate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.