去甲氟西汀
TL;DR: 去甲氟西汀 (CAS 83891-03-6) is a chemical compound with molecular formula C16H16F3NO and molecular weight 295.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
去甲氟西汀
3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Also Known As: Norfluoxetine, Desmethylfluoxetine, Norfluoxetin, (S)-Norfluoxetine, Seproxetine HCl
| Molecular Formula | C16H16F3NO |
|---|---|
| Molecular Weight | 295.12 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 35.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 295.1184 |
| Heavy Atoms | 21 |
| Complexity | 294.0 |
Chemical Identifiers
| CAS Number | 83891-03-6 |
|---|---|
| SMILES | C1=CC=C(C=C1)C(CCN)OC2=CC=C(C=C2)C(F)(F)F |
| InChIKey | WIQRCHMSJFFONW-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
去甲氟西汀 (CAS 83891-03-6), with molecular formula C16H16F3NO and molecular weight 295.12 g/mol. IUPAC: 3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine.
Chemical Property Profile of 去甲氟西汀
Property Insights of 去甲氟西汀
The XLogP value of 3.5 indicates that 去甲氟西汀 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.3 Ų, 去甲氟西汀 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 去甲氟西汀 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 去甲氟西汀?
The CAS number of 去甲氟西汀 is 83891-03-6.
What is the molecular formula of 去甲氟西汀?
The molecular formula of 去甲氟西汀 is C16H16F3NO.
What is the molecular weight of 去甲氟西汀?
The molecular weight of 去甲氟西汀 is 295.12 g/mol.
Where can I buy 去甲氟西汀?
You can request a quote for 去甲氟西汀 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 去甲氟西汀?
Yes, KEHONG BIO provides custom synthesis services for 去甲氟西汀 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.