CGP-12177 structure

CGP-12177

TL;DR: CGP-12177 (CAS 81047-99-6) is a chemical compound with molecular formula C14H21N3O3 and molecular weight 279.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

CGP-12177

4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one

Also Known As: Tbhpbo, Cgp 12177, Cgp 12177A, 1,4-Dibromo-2-butene, Spectrum4_000777

CAS: 81047-99-6
Molecular Formula C14H21N3O3
Molecular Weight 279.16 g/mol
LogP 0.5
Topological Polar Surface Area 82.6 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 4
Rotatable Bonds 6
Exact Mass 279.1583
Heavy Atoms 20
Complexity 343.0

Chemical Identifiers

CAS Number 81047-99-6
SMILES CC(C)(C)NCC(COC1=CC=CC2=C1NC(=O)N2)O
InChIKey UMQUQWCJKFOUGV-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Heterocyclic Building Blocks (4 patents) Pharmaceutical Intermediates (63 patents)

Product Overview

CGP-12177 (CAS 81047-99-6), with molecular formula C14H21N3O3 and molecular weight 279.16 g/mol. IUPAC: 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of CGP-12177

XLogP
0.5
TPSA (Topological Polar Surface Area)
82.6
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
4
Rotatable Bonds
6
Heavy Atoms
20
Complexity
343.0
Exact Mass
279.1583
Monoisotopic Mass
279.1583
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of CGP-12177

The XLogP value of 0.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for CGP-12177. The TPSA of 82.6 Ų falls within the moderate polarity range, balancing permeability and solubility for CGP-12177. Following Lipinski's Rule of Five, Tbhpbo has 4 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tbhpbo?

The CAS number of Tbhpbo is 81047-99-6.

What is the molecular formula of Tbhpbo?

The molecular formula of Tbhpbo is C14H21N3O3.

What is the molecular weight of Tbhpbo?

The molecular weight of Tbhpbo is 279.16 g/mol.

Where can I buy Tbhpbo?

You can request a quote for Tbhpbo directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tbhpbo?

Yes, KEHONG BIO provides custom synthesis services for Tbhpbo and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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