洛克他汀酸 structure

洛克他汀酸

TL;DR: 洛克他汀酸 (CAS 76684-89-4) is a chemical compound with molecular formula C15H26N2O5 and molecular weight 314.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

洛克他汀酸

3-[[4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid

Also Known As: Loxistatin acid, Vismodegib, e-64c, E 64c, Loxistatin Acid (E-64C)

CAS: 76684-89-4
Molecular Formula C15H26N2O5
Molecular Weight 314.18 g/mol
LogP 1.6
Topological Polar Surface Area 108.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 5
Rotatable Bonds 9
Exact Mass 314.18417
Heavy Atoms 22
Complexity 422.0

Chemical Identifiers

CAS Number 76684-89-4
SMILES CC(C)CCNC(=O)C(CC(C)C)NC(=O)C1C(O1)C(=O)O
InChIKey SCMSYZJDIQPSDI-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (1 patents)

Product Overview

洛克他汀酸 (CAS 76684-89-4), with molecular formula C15H26N2O5 and molecular weight 314.18 g/mol. IUPAC: 3-[[4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 洛克他汀酸

XLogP
1.6
TPSA (Topological Polar Surface Area)
108.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
5
Rotatable Bonds
9
Heavy Atoms
22
Complexity
422.0
Exact Mass
314.18417
Monoisotopic Mass
314.18417
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 洛克他汀酸

The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 洛克他汀酸. The TPSA of 108.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 洛克他汀酸. Following Lipinski's Rule of Five, L-trans-Epoxysuccinyl-Leu-3-methylbutylamide has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?

The CAS number of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide is 76684-89-4.

What is the molecular formula of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?

The molecular formula of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide is C15H26N2O5.

What is the molecular weight of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?

The molecular weight of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide is 314.18 g/mol.

Where can I buy L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?

You can request a quote for L-trans-Epoxysuccinyl-Leu-3-methylbutylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?

Yes, KEHONG BIO provides custom synthesis services for L-trans-Epoxysuccinyl-Leu-3-methylbutylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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