尼伐地平
TL;DR: 尼伐地平 (CAS 75530-68-6) is a chemical compound with molecular formula C19H19N3O6 and molecular weight 385.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
尼伐地平
3-O-methyl 5-O-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: nilvadipine, Escor, Nivadil, Nivadipine, Nilvadipino
| Molecular Formula | C19H19N3O6 |
|---|---|
| Molecular Weight | 385.13 g/mol |
| LogP | 2.9 |
| Topological Polar Surface Area | 134.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 385.12738 |
| Heavy Atoms | 28 |
| Complexity | 783.0 |
Chemical Identifiers
| CAS Number | 75530-68-6 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C#N)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC(C)C |
| InChIKey | FAIIFDPAEUKBEP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 18 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
尼伐地平 (CAS 75530-68-6), with molecular formula C19H19N3O6 and molecular weight 385.13 g/mol. IUPAC: 3-O-methyl 5-O-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of 尼伐地平
Property Insights of 尼伐地平
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 尼伐地平. The TPSA of 134.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 尼伐地平. Following Lipinski's Rule of Five, 尼伐地平 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 尼伐地平?
The CAS number of 尼伐地平 is 75530-68-6.
What is the molecular formula of 尼伐地平?
The molecular formula of 尼伐地平 is C19H19N3O6.
What is the molecular weight of 尼伐地平?
The molecular weight of 尼伐地平 is 385.13 g/mol.
Where can I buy 尼伐地平?
You can request a quote for 尼伐地平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 尼伐地平?
Yes, KEHONG BIO provides custom synthesis services for 尼伐地平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.