伏拉塞替
TL;DR: 伏拉塞替 (CAS 755038-65-4) is a chemical compound with molecular formula C15H29N5O5 and molecular weight 359.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
伏拉塞替
4-[[1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-4-oxobutanoic acid
Also Known As: Volasertib, 4-[[1-(4-guanidinobutylcarbamoyl)-3-methyl-butyl]amino]-3-hydroxy-4-oxo-butanoic acid, 4-[[1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-4-oxobutanoic acid, 4-{[1-({4-[(diaminomethylidene)amino]butyl}amino)-4-methyl-1-oxopentan-2-yl]amino}-3-hydroxy-4-oxobutanoic acid, N-((1r,4r)-4-(4-(cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylamino)-3-methoxybenzamide
| Molecular Formula | C15H29N5O5 |
|---|---|
| Molecular Weight | 359.22 g/mol |
| LogP | -1.3 |
| Topological Polar Surface Area | 180.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 12 |
| Exact Mass | 359.21686 |
| Heavy Atoms | 25 |
| Complexity | 477.0 |
Chemical Identifiers
| CAS Number | 755038-65-4 |
|---|---|
| SMILES | CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C(CC(=O)O)O |
| InChIKey | QPQNJAXBPHVASB-UHFFFAOYSA-N |
Product Overview
伏拉塞替 (CAS 755038-65-4), with molecular formula C15H29N5O5 and molecular weight 359.22 g/mol. IUPAC: 4-[[1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-4-oxobutanoic acid.
Chemical Property Profile of 伏拉塞替
Property Insights of 伏拉塞替
The XLogP value of -1.3 indicates that 伏拉塞替 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 180.0 Ų indicates high polarity, suggesting 伏拉塞替 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Volasertib has 6 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Volasertib?
The CAS number of Volasertib is 755038-65-4.
What is the molecular formula of Volasertib?
The molecular formula of Volasertib is C15H29N5O5.
What is the molecular weight of Volasertib?
The molecular weight of Volasertib is 359.22 g/mol.
Where can I buy Volasertib?
You can request a quote for Volasertib directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Volasertib?
Yes, KEHONG BIO provides custom synthesis services for Volasertib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.