非洛地平
TL;DR: 非洛地平 (CAS 72509-76-3) is a chemical compound with molecular formula C18H19Cl2NO4 and molecular weight 383.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
非洛地平
5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: felodipine, Plendil, Flodil, Splendil, Feloday
| Molecular Formula | C18H19Cl2NO4 |
|---|---|
| Molecular Weight | 383.07 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 64.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 383.06912 |
| Heavy Atoms | 25 |
| Complexity | 614.0 |
| Melting Point | 145 |
| Solubility | 19.7 |
Chemical Identifiers
| CAS Number | 72509-76-3 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C |
| InChIKey | RZTAMFZIAATZDJ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 16 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
非洛地平 (CAS 72509-76-3), with molecular formula C18H19Cl2NO4 and molecular weight 383.07 g/mol. IUPAC: 5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of 非洛地平
Property Insights of 非洛地平
The XLogP value of 3.9 indicates that 非洛地平 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 非洛地平. Following Lipinski's Rule of Five, 非洛地平 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 非洛地平?
The CAS number of 非洛地平 is 72509-76-3.
What is the molecular formula of 非洛地平?
The molecular formula of 非洛地平 is C18H19Cl2NO4.
What is the molecular weight of 非洛地平?
The molecular weight of 非洛地平 is 383.07 g/mol.
Where can I buy 非洛地平?
You can request a quote for 非洛地平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 非洛地平?
Yes, KEHONG BIO provides custom synthesis services for 非洛地平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.