去甲替林
TL;DR: 去甲替林 (CAS 72-69-5) is a chemical compound with molecular formula C19H21N and molecular weight 263.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
去甲替林
N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
Also Known As: nortriptyline, Noramitriptyline, Desitriptilina, Aventyl, Avantyl
| Molecular Formula | C19H21N |
|---|---|
| Molecular Weight | 263.17 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 12.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 3 |
| Exact Mass | 263.1674 |
| Heavy Atoms | 20 |
| Complexity | 307.0 |
| Melting Point | 58 |
| Boiling Point | 396.62 |
| Solubility | 0.00087 |
Chemical Identifiers
| CAS Number | 72-69-5 |
|---|---|
| SMILES | CNCCC=C1C2=CC=CC=C2CCC3=CC=CC=C31 |
| InChIKey | PHVGLTMQBUFIQQ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 19 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
去甲替林 (CAS 72-69-5), with molecular formula C19H21N and molecular weight 263.17 g/mol. IUPAC: N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine.
Chemical Property Profile of 去甲替林
Property Insights of 去甲替林
The XLogP value of 4.5 indicates that 去甲替林 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.0 Ų, 去甲替林 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 去甲替林 has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 去甲替林?
The CAS number of 去甲替林 is 72-69-5.
What is the molecular formula of 去甲替林?
The molecular formula of 去甲替林 is C19H21N.
What is the molecular weight of 去甲替林?
The molecular weight of 去甲替林 is 263.17 g/mol.
Where can I buy 去甲替林?
You can request a quote for 去甲替林 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 去甲替林?
Yes, KEHONG BIO provides custom synthesis services for 去甲替林 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.