Yohimbine Hydrochloride structure

Yohimbine Hydrochloride

TL;DR: Yohimbine Hydrochloride (CAS 65-19-0) is a chemical compound with molecular formula C21H27ClN2O3 and molecular weight 390.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride

Also Known As: YOHIMBINE HYDROCHLORIDE, Yohimbine HCl, Antagonil, Yohimbe, Aphrodine hydrochloride

CAS: 65-19-0
Molecular Formula C21H27ClN2O3
Molecular Weight 390.17 g/mol
LogP 3.07
Topological Polar Surface Area 65.6 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 390.17102
Heavy Atoms 27
Complexity 555.0

Chemical Identifiers

CAS Number 65-19-0
SMILES COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
InChIKey PIPZGJSEDRMUAW-VJDCAHTMSA-N

Patent-Derived Application Labels

Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (7 patents) Analytical Reagents (1 patents) Biotechnology (2 patents) Food Additives (1 patents) Heterocyclic Building Blocks (85 patents) +7 more

Product Overview

Yohimbine Hydrochloride (CAS 65-19-0), with molecular formula C21H27ClN2O3 and molecular weight 390.17 g/mol. IUPAC: methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Yohimbine Hydrochloride

XLogP
3.07
TPSA (Topological Polar Surface Area)
65.6
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
27
Complexity
555.0
Exact Mass
390.17102
Monoisotopic Mass
390.17102
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Yohimbine Hydrochloride

The XLogP value of 3.07 indicates that Yohimbine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Yohimbine Hydrochloride. Following Lipinski's Rule of Five, Yohimbine Hydrochloride has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Yohimbine Hydrochloride?

The CAS number of Yohimbine Hydrochloride is 65-19-0.

What is the molecular formula of Yohimbine Hydrochloride?

The molecular formula of Yohimbine Hydrochloride is C21H27ClN2O3.

What is the molecular weight of Yohimbine Hydrochloride?

The molecular weight of Yohimbine Hydrochloride is 390.17 g/mol.

Where can I buy Yohimbine Hydrochloride?

You can request a quote for Yohimbine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Yohimbine Hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Yohimbine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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