尼索地平
TL;DR: 尼索地平 (CAS 63675-72-9) is a chemical compound with molecular formula C20H24N2O6 and molecular weight 388.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
尼索地平
3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: nisoldipine, Sular, Nisocor, Nisoldipin, Baymycard
| Molecular Formula | C20H24N2O6 |
|---|---|
| Molecular Weight | 388.16 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 110.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 388.16342 |
| Heavy Atoms | 28 |
| Complexity | 704.0 |
| Solubility | 5.77e-03 g/L |
Chemical Identifiers
| CAS Number | 63675-72-9 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCC(C)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC |
| InChIKey | VKQFCGNPDRICFG-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 16 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
尼索地平 (CAS 63675-72-9), with molecular formula C20H24N2O6 and molecular weight 388.16 g/mol. IUPAC: 3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of 尼索地平
Property Insights of 尼索地平
The XLogP value of 3.3 indicates that Nisoldipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 尼索地平. Following Lipinski's Rule of Five, Nisoldipine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nisoldipine?
The CAS number of Nisoldipine is 63675-72-9.
What is the molecular formula of Nisoldipine?
The molecular formula of Nisoldipine is C20H24N2O6.
What is the molecular weight of Nisoldipine?
The molecular weight of Nisoldipine is 388.16 g/mol.
Where can I buy Nisoldipine?
You can request a quote for Nisoldipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nisoldipine?
Yes, KEHONG BIO provides custom synthesis services for Nisoldipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.