定脈平
TL;DR: 定脈平 (CAS 63590-64-7) is a chemical compound with molecular formula C19H25N5O4 and molecular weight 387.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
定脈平
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone
Also Known As: terazosin, Terazosine, Fosfomic, Terazosin hydrochloride, Terazosina
| Molecular Formula | C19H25N5O4 |
|---|---|
| Molecular Weight | 387.19 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 103.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 387.19064 |
| Heavy Atoms | 28 |
| Complexity | 544.0 |
| Melting Point | 271-274 |
| Solubility | 1.50e+00 g/L |
Chemical Identifiers
| CAS Number | 63590-64-7 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC |
| InChIKey | VCKUSRYTPJJLNI-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 16 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
定脈平 (CAS 63590-64-7), with molecular formula C19H25N5O4 and molecular weight 387.19 g/mol. IUPAC: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone.
Chemical Property Profile of 定脈平
Property Insights of 定脈平
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 定脈平. The TPSA of 103.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 定脈平. Following Lipinski's Rule of Five, 定脈平 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 定脈平?
The CAS number of 定脈平 is 63590-64-7.
What is the molecular formula of 定脈平?
The molecular formula of 定脈平 is C19H25N5O4.
What is the molecular weight of 定脈平?
The molecular weight of 定脈平 is 387.19 g/mol.
Where can I buy 定脈平?
You can request a quote for 定脈平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 定脈平?
Yes, KEHONG BIO provides custom synthesis services for 定脈平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.