帕唑帕尼盐酸盐
TL;DR: 帕唑帕尼盐酸盐 (CAS 635702-64-6) is a chemical compound with molecular formula C30H42O6 and molecular weight 498.30 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
帕唑帕尼盐酸盐
[1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] deca-3,5-dienoate
Also Known As: pazopanib HCl, 4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl deca-3,5-dienoate, 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide hydrochloride
| Molecular Formula | C30H42O6 |
|---|---|
| Molecular Weight | 498.30 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 104.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 498.29813 |
| Heavy Atoms | 36 |
| Complexity | 1030.0 |
Chemical Identifiers
| CAS Number | 635702-64-6 |
|---|---|
| SMILES | CCCCC=CC=CCC(=O)OC12CC(C3(C(C1C2(C)C)C=C(CC4(C3C=C(C4=O)C)O)CO)O)C |
| InChIKey | AZEXNJIEBDRVJS-UHFFFAOYSA-N |
Product Overview
帕唑帕尼盐酸盐 (CAS 635702-64-6), with molecular formula C30H42O6 and molecular weight 498.30 g/mol. IUPAC: [1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] deca-3,5-dienoate.
Chemical Property Profile of 帕唑帕尼盐酸盐
Property Insights of 帕唑帕尼盐酸盐
The XLogP value of 3.8 indicates that pazopanib HCl is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 帕唑帕尼盐酸盐. Following Lipinski's Rule of Five, pazopanib HCl has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of pazopanib HCl?
The CAS number of pazopanib HCl is 635702-64-6.
What is the molecular formula of pazopanib HCl?
The molecular formula of pazopanib HCl is C30H42O6.
What is the molecular weight of pazopanib HCl?
The molecular weight of pazopanib HCl is 498.30 g/mol.
Where can I buy pazopanib HCl?
You can request a quote for pazopanib HCl directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for pazopanib HCl?
Yes, KEHONG BIO provides custom synthesis services for pazopanib HCl and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.