二翁科菲碱A
TL;DR: 二翁科菲碱A (CAS 60142-17-8) is a chemical compound with molecular formula C24H27NO3 and molecular weight 377.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
二翁科菲碱A
7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol
Also Known As: Dioncophylline A, Dioncophyllin A, clozapine, 7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol, 7-(4,5-Dimethoxy-2-methyl-1-naphthyl)-1,3-dimethyl-1,2,3,4-tetrahydro-8-isoquinolinol #
| Molecular Formula | C24H27NO3 |
|---|---|
| Molecular Weight | 377.20 g/mol |
| LogP | 5.0 |
| Topological Polar Surface Area | 50.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 377.1991 |
| Heavy Atoms | 28 |
| Complexity | 528.0 |
Chemical Identifiers
| CAS Number | 60142-17-8 |
|---|---|
| SMILES | CC1CC2=C(C(N1)C)C(=C(C=C2)C3=C4C=CC=C(C4=C(C=C3C)OC)OC)O |
| InChIKey | MXIZZLBQRBAZEX-UHFFFAOYSA-N |
Product Overview
二翁科菲碱A (CAS 60142-17-8), with molecular formula C24H27NO3 and molecular weight 377.20 g/mol. IUPAC: 7-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol.
Chemical Property Profile of 二翁科菲碱A
Property Insights of 二翁科菲碱A
The XLogP value of 5.0 indicates that 二翁科菲碱A is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.7 Ų, 二翁科菲碱A exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 二翁科菲碱A has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 二翁科菲碱A?
The CAS number of 二翁科菲碱A is 60142-17-8.
What is the molecular formula of 二翁科菲碱A?
The molecular formula of 二翁科菲碱A is C24H27NO3.
What is the molecular weight of 二翁科菲碱A?
The molecular weight of 二翁科菲碱A is 377.20 g/mol.
Where can I buy 二翁科菲碱A?
You can request a quote for 二翁科菲碱A directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 二翁科菲碱A?
Yes, KEHONG BIO provides custom synthesis services for 二翁科菲碱A and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.