乙酰唑胺
TL;DR: 乙酰唑胺 (CAS 59-66-5) is a chemical compound with molecular formula C4H6N4O3S2 and molecular weight 221.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
乙酰唑胺
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
Also Known As: acetazolamide, Acetamox, Diamox, Glaupax, Edemox
| Molecular Formula | C4H6N4O3S2 |
|---|---|
| Molecular Weight | 221.99 g/mol |
| LogP | -0.3 |
| Topological Polar Surface Area | 152.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 221.98813 |
| Heavy Atoms | 13 |
| Complexity | 297.0 |
| Melting Point | 496 to 258.9 °C (effervescence) |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992) |
Chemical Identifiers
| CAS Number | 59-66-5 |
|---|---|
| SMILES | CC(=O)NC1=NN=C(S1)S(=O)(=O)N |
| InChIKey | BZKPWHYZMXOIDC-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 18 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
乙酰唑胺 (CAS 59-66-5), with molecular formula C4H6N4O3S2 and molecular weight 221.99 g/mol. IUPAC: N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide.
Chemical Property Profile of 乙酰唑胺
Property Insights of 乙酰唑胺
The XLogP value of -0.3 indicates that 乙酰唑胺 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 152.0 Ų indicates high polarity, suggesting 乙酰唑胺 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 乙酰唑胺 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 乙酰唑胺?
The CAS number of 乙酰唑胺 is 59-66-5.
What is the molecular formula of 乙酰唑胺?
The molecular formula of 乙酰唑胺 is C4H6N4O3S2.
What is the molecular weight of 乙酰唑胺?
The molecular weight of 乙酰唑胺 is 221.99 g/mol.
Where can I buy 乙酰唑胺?
You can request a quote for 乙酰唑胺 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 乙酰唑胺?
Yes, KEHONG BIO provides custom synthesis services for 乙酰唑胺 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.