普樂明
TL;DR: 普樂明 (CAS 58-38-8) is a chemical compound with molecular formula C20H24ClN3S and molecular weight 373.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
普樂明
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
Also Known As: prochlorperazine, Prochlorperazin, Chlormeprazine, Chlorperazine, Procloperazine
| Molecular Formula | C20H24ClN3S |
|---|---|
| Molecular Weight | 373.14 g/mol |
| LogP | 4.9 |
| Topological Polar Surface Area | 35.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 373.13794 |
| Heavy Atoms | 25 |
| Complexity | 429.0 |
| Melting Point | 228 |
| Solubility | 15 |
Chemical Identifiers
| CAS Number | 58-38-8 |
|---|---|
| SMILES | CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl |
| InChIKey | WIKYUJGCLQQFNW-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 18 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
普樂明 (CAS 58-38-8), with molecular formula C20H24ClN3S and molecular weight 373.14 g/mol. IUPAC: 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine.
Chemical Property Profile of 普樂明
Property Insights of 普樂明
The XLogP value of 4.9 indicates that 普樂明 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.0 Ų, 普樂明 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 普樂明 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 普樂明?
The CAS number of 普樂明 is 58-38-8.
What is the molecular formula of 普樂明?
The molecular formula of 普樂明 is C20H24ClN3S.
What is the molecular weight of 普樂明?
The molecular weight of 普樂明 is 373.14 g/mol.
Where can I buy 普樂明?
You can request a quote for 普樂明 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 普樂明?
Yes, KEHONG BIO provides custom synthesis services for 普樂明 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.