Dodecamethylcyclohexasiloxane
TL;DR: Dodecamethylcyclohexasiloxane (CAS 540-97-6) is a chemical compound with molecular formula C12H36O6Si6 and molecular weight 444.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
Also Known As: DODECAMETHYLCYCLOHEXASILOXANE, Cyclomethicone 6, Cyclohexasiloxane, Cyclohexasiloxane, dodecamethyl-, Polysiloxane D6 CRS
| Molecular Formula | C12H36O6Si6 |
|---|---|
| Molecular Weight | 444.11 g/mol |
| LogP | 4.31 |
| Topological Polar Surface Area | 55.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 0 |
| Exact Mass | 444.11276 |
| Heavy Atoms | 24 |
| Complexity | 320.0 |
| Melting Point | -3 °C |
| Boiling Point | 245 °C |
| Density | 0.9672 g/cu cm at 25 °C |
| Solubility | In water, 0.0051 mg/L at 23 °C |
| Flash Point | 91 °C (91.1 °C) - closed cup |
| Vapor Pressure | 0.0169 mm Hg at 25 °C |
| Refractive Index | = 1.4015 at 20 °C |
Chemical Identifiers
| CAS Number | 540-97-6 |
|---|---|
| SMILES | C[Si]1(O[Si](O[Si](O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C)(C)C)(C)C)C |
| InChIKey | IUMSDRXLFWAGNT-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 21 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Dodecamethylcyclohexasiloxane (CAS 540-97-6), with molecular formula C12H36O6Si6 and molecular weight 444.11 g/mol. IUPAC: 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane.
Chemical Property Profile of Dodecamethylcyclohexasiloxane
Property Insights of Dodecamethylcyclohexasiloxane
The XLogP value of 4.31 indicates that Dodecamethylcyclohexasiloxane is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.4 Ų, Dodecamethylcyclohexasiloxane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dodecamethylcyclohexasiloxane has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dodecamethylcyclohexasiloxane?
The CAS number of Dodecamethylcyclohexasiloxane is 540-97-6.
What is the molecular formula of Dodecamethylcyclohexasiloxane?
The molecular formula of Dodecamethylcyclohexasiloxane is C12H36O6Si6.
What is the molecular weight of Dodecamethylcyclohexasiloxane?
The molecular weight of Dodecamethylcyclohexasiloxane is 444.11 g/mol.
Where can I buy Dodecamethylcyclohexasiloxane?
You can request a quote for Dodecamethylcyclohexasiloxane directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dodecamethylcyclohexasiloxane?
Yes, KEHONG BIO provides custom synthesis services for Dodecamethylcyclohexasiloxane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.