Estra-1,3,5(10)-trien-3-ol structure

Estra-1,3,5(10)-trien-3-ol

TL;DR: Estra-1,3,5(10)-trien-3-ol (CAS 53-63-4) is a chemical compound with molecular formula C18H24O and molecular weight 256.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,9S,13S,14S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-ol

Also Known As: 17-Deoxyestradiol, 17-Deoxyestrone, 17-Desoxyestradiol, Deoxoestrone, 17-Deoxyoestrone

CAS: 53-63-4
Molecular Formula C18H24O
Molecular Weight 256.18 g/mol
LogP 5.6
Topological Polar Surface Area 20.2 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 1
Rotatable Bonds 0
Exact Mass 256.1827
Heavy Atoms 19
Complexity 352.0

Chemical Identifiers

CAS Number 53-63-4
SMILES C[C@@]12CCC[C@H]1[C@@H]3CCC4=C([C@H]3CC2)C=CC(=C4)O
InChIKey HJKVPZJVBHWFCQ-BDXSIMOUSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (1 patents) Heterocyclic Building Blocks (109 patents) Organic Building Blocks (1 patents) Pharmaceutical Intermediates (131 patents)

Product Overview

Estra-1,3,5(10)-trien-3-ol (CAS 53-63-4), with molecular formula C18H24O and molecular weight 256.18 g/mol. IUPAC: (8S,9S,13S,14S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Estra-1,3,5(10)-trien-3-ol

XLogP
5.6
TPSA (Topological Polar Surface Area)
20.2
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
1
Rotatable Bonds
0
Heavy Atoms
19
Complexity
352.0
Exact Mass
256.1827
Monoisotopic Mass
256.1827
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Estra-1,3,5(10)-trien-3-ol

The XLogP value of 5.6 indicates that Estra-1,3,5(10)-trien-3-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.2 Ų, Estra-1,3,5(10)-trien-3-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Estra-1,3,5(10)-trien-3-ol has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Estra-1,3,5(10)-trien-3-ol?

The CAS number of Estra-1,3,5(10)-trien-3-ol is 53-63-4.

What is the molecular formula of Estra-1,3,5(10)-trien-3-ol?

The molecular formula of Estra-1,3,5(10)-trien-3-ol is C18H24O.

What is the molecular weight of Estra-1,3,5(10)-trien-3-ol?

The molecular weight of Estra-1,3,5(10)-trien-3-ol is 256.18 g/mol.

Where can I buy Estra-1,3,5(10)-trien-3-ol?

You can request a quote for Estra-1,3,5(10)-trien-3-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Estra-1,3,5(10)-trien-3-ol?

Yes, KEHONG BIO provides custom synthesis services for Estra-1,3,5(10)-trien-3-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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