Tetrahydrocortisone
TL;DR: Tetrahydrocortisone (CAS 53-05-4) is a chemical compound with molecular formula C21H32O5 and molecular weight 364.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
Also Known As: TETRAHYDROCORTISONE, Urocortisone, Tetrahydro E, Tetrahydro Cortisone, Tetrahydrocompound E
| Molecular Formula | C21H32O5 |
|---|---|
| Molecular Weight | 364.22 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 364.22498 |
| Heavy Atoms | 26 |
| Complexity | 632.0 |
Chemical Identifiers
| CAS Number | 53-05-4 |
|---|---|
| SMILES | C[C@]12CC[C@H](C[C@H]1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O |
| InChIKey | SYGWGHVTLUBCEM-ZIZPXRJBSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tetrahydrocortisone (CAS 53-05-4), with molecular formula C21H32O5 and molecular weight 364.22 g/mol. IUPAC: (3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one.
Chemical Property Profile of Tetrahydrocortisone
Property Insights of Tetrahydrocortisone
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tetrahydrocortisone. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Tetrahydrocortisone. Following Lipinski's Rule of Five, Tetrahydrocortisone has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tetrahydrocortisone?
The CAS number of Tetrahydrocortisone is 53-05-4.
What is the molecular formula of Tetrahydrocortisone?
The molecular formula of Tetrahydrocortisone is C21H32O5.
What is the molecular weight of Tetrahydrocortisone?
The molecular weight of Tetrahydrocortisone is 364.22 g/mol.
Where can I buy Tetrahydrocortisone?
You can request a quote for Tetrahydrocortisone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tetrahydrocortisone?
Yes, KEHONG BIO provides custom synthesis services for Tetrahydrocortisone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.