沙利度胺
TL;DR: 沙利度胺 (CAS 50-35-1) is a chemical compound with molecular formula C13H10N2O4 and molecular weight 258.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
沙利度胺
2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Also Known As: thalidomide, Thalomid, Contergan, Pantosediv, Distaval
| Molecular Formula | C13H10N2O4 |
|---|---|
| Molecular Weight | 258.06 g/mol |
| LogP | 0.3 |
| Topological Polar Surface Area | 83.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 258.06406 |
| Heavy Atoms | 19 |
| Complexity | 449.0 |
| Melting Point | 516 to 271.1 °C |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992) |
Chemical Identifiers
| CAS Number | 50-35-1 |
|---|---|
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O |
| InChIKey | UEJJHQNACJXSKW-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 21 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
沙利度胺 (CAS 50-35-1), with molecular formula C13H10N2O4 and molecular weight 258.06 g/mol. IUPAC: 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione.
Chemical Property Profile of 沙利度胺
Property Insights of 沙利度胺
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 沙利度胺. The TPSA of 83.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 沙利度胺. Following Lipinski's Rule of Five, 沙利度胺 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 沙利度胺?
The CAS number of 沙利度胺 is 50-35-1.
What is the molecular formula of 沙利度胺?
The molecular formula of 沙利度胺 is C13H10N2O4.
What is the molecular weight of 沙利度胺?
The molecular weight of 沙利度胺 is 258.06 g/mol.
Where can I buy 沙利度胺?
You can request a quote for 沙利度胺 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 沙利度胺?
Yes, KEHONG BIO provides custom synthesis services for 沙利度胺 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.