地塞米松
TL;DR: 地塞米松 (CAS 50-02-2) is a chemical compound with molecular formula C22H29FO5 and molecular weight 392.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
地塞米松
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Also Known As: dexamethasone, Decadron, Maxidex, Dexamethazone, Cortisumman
| Molecular Formula | C22H29FO5 |
|---|---|
| Molecular Weight | 392.20 g/mol |
| LogP | 1.9 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 392.1999 |
| Heavy Atoms | 28 |
| Complexity | 805.0 |
| Melting Point | 504 to 263.9 °C |
| Solubility | less than 1 mg/mL at 77 °F (NTP, 1992) |
Chemical Identifiers
| CAS Number | 50-02-2 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C |
| InChIKey | UREBDLICKHMUKA-CXSFZGCWSA-N |
Patent-Derived Application Labels
Derived from 22 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
地塞米松 (CAS 50-02-2), with molecular formula C22H29FO5 and molecular weight 392.20 g/mol. IUPAC: (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 地塞米松
Property Insights of 地塞米松
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 地塞米松. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 地塞米松. Following Lipinski's Rule of Five, 地塞米松 has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 地塞米松?
The CAS number of 地塞米松 is 50-02-2.
What is the molecular formula of 地塞米松?
The molecular formula of 地塞米松 is C22H29FO5.
What is the molecular weight of 地塞米松?
The molecular weight of 地塞米松 is 392.20 g/mol.
Where can I buy 地塞米松?
You can request a quote for 地塞米松 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 地塞米松?
Yes, KEHONG BIO provides custom synthesis services for 地塞米松 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.