Dihydroberberine
TL;DR: Dihydroberberine (CAS 483-15-8) is a chemical compound with molecular formula C20H19NO4 and molecular weight 337.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
16,17-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(21),2,4(8),9,15(20),16,18-heptaene
Also Known As: Dihydroberberine, Dihydroberbine, Dihydroumbellatine, Lambertine, 7,8-Dihydroberberine
| Molecular Formula | C20H19NO4 |
|---|---|
| Molecular Weight | 337.13 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 40.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 337.1314 |
| Heavy Atoms | 25 |
| Complexity | 538.0 |
| Melting Point | 163 - 164 °C |
Chemical Identifiers
| CAS Number | 483-15-8 |
|---|---|
| SMILES | COC1=C(C2=C(C=C1)C=C3C4=CC5=C(C=C4CCN3C2)OCO5)OC |
| InChIKey | FZAGOOYMTPGPGF-UHFFFAOYSA-N |
Product Overview
Dihydroberberine (CAS 483-15-8), with molecular formula C20H19NO4 and molecular weight 337.13 g/mol. IUPAC: 16,17-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(21),2,4(8),9,15(20),16,18-heptaene.
Chemical Property Profile of Dihydroberberine
Property Insights of Dihydroberberine
The XLogP value of 3.5 indicates that Dihydroberberine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.2 Ų, Dihydroberberine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dihydroberberine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dihydroberberine?
The CAS number of Dihydroberberine is 483-15-8.
What is the molecular formula of Dihydroberberine?
The molecular formula of Dihydroberberine is C20H19NO4.
What is the molecular weight of Dihydroberberine?
The molecular weight of Dihydroberberine is 337.13 g/mol.
Where can I buy Dihydroberberine?
You can request a quote for Dihydroberberine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dihydroberberine?
Yes, KEHONG BIO provides custom synthesis services for Dihydroberberine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.