克拉屈滨
TL;DR: 克拉屈滨 (CAS 4291-63-8) is a chemical compound with molecular formula C10H12ClN5O3 and molecular weight 285.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
克拉屈滨
5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Also Known As: Cladribine, null, Leustatin, Leustat, 2-Chloro-2'-deoxyadenosine
| Molecular Formula | C10H12ClN5O3 |
|---|---|
| Molecular Weight | 285.06 g/mol |
| LogP | 0.8 |
| Topological Polar Surface Area | 119.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 285.06287 |
| Heavy Atoms | 19 |
| Complexity | 338.0 |
Chemical Identifiers
| CAS Number | 4291-63-8 |
|---|---|
| SMILES | C1C(C(OC1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O |
| InChIKey | PTOAARAWEBMLNO-UHFFFAOYSA-N |
Product Overview
克拉屈滨 (CAS 4291-63-8), with molecular formula C10H12ClN5O3 and molecular weight 285.06 g/mol. IUPAC: 5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol.
Chemical Property Profile of 克拉屈滨
Property Insights of 克拉屈滨
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 克拉屈滨. The TPSA of 119.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 克拉屈滨. Following Lipinski's Rule of Five, 克拉屈滨 has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 克拉屈滨?
The CAS number of 克拉屈滨 is 4291-63-8.
What is the molecular formula of 克拉屈滨?
The molecular formula of 克拉屈滨 is C10H12ClN5O3.
What is the molecular weight of 克拉屈滨?
The molecular weight of 克拉屈滨 is 285.06 g/mol.
Where can I buy 克拉屈滨?
You can request a quote for 克拉屈滨 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 克拉屈滨?
Yes, KEHONG BIO provides custom synthesis services for 克拉屈滨 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.