纳多洛尔
TL;DR: 纳多洛尔 (CAS 42200-33-9) is a chemical compound with molecular formula C17H27NO4 and molecular weight 309.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
纳多洛尔
5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol
Also Known As: nadolol, Solgol, Corgard, Anabet, Nadololum
| Molecular Formula | C17H27NO4 |
|---|---|
| Molecular Weight | 309.19 g/mol |
| LogP | 0.7 |
| Topological Polar Surface Area | 82.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 309.194 |
| Heavy Atoms | 22 |
| Complexity | 344.0 |
| Solubility | >46.4 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 42200-33-9 |
|---|---|
| SMILES | CC(C)(C)NCC(COC1=CC=CC2=C1CC(C(C2)O)O)O |
| InChIKey | VWPOSFSPZNDTMJ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
纳多洛尔 (CAS 42200-33-9), with molecular formula C17H27NO4 and molecular weight 309.19 g/mol. IUPAC: 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol.
Chemical Property Profile of 纳多洛尔
Property Insights of 纳多洛尔
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 纳多洛尔. The TPSA of 82.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 纳多洛尔. Following Lipinski's Rule of Five, 纳多洛尔 has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 纳多洛尔?
The CAS number of 纳多洛尔 is 42200-33-9.
What is the molecular formula of 纳多洛尔?
The molecular formula of 纳多洛尔 is C17H27NO4.
What is the molecular weight of 纳多洛尔?
The molecular weight of 纳多洛尔 is 309.19 g/mol.
Where can I buy 纳多洛尔?
You can request a quote for 纳多洛尔 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 纳多洛尔?
Yes, KEHONG BIO provides custom synthesis services for 纳多洛尔 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.