雷公藤内酯
TL;DR: 雷公藤内酯 (CAS 38748-32-2) is a chemical compound with molecular formula C20H24O6 and molecular weight 360.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
雷公藤内酯
8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
Also Known As: triptolide, Triptolid, Triptolide [M+H]+, Triptolidefrom Tripterygium wilfordii, PG 490
| Molecular Formula | C20H24O6 |
|---|---|
| Molecular Weight | 360.16 g/mol |
| LogP | 0.2 |
| Topological Polar Surface Area | 84.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 360.1573 |
| Heavy Atoms | 26 |
| Complexity | 819.0 |
Chemical Identifiers
| CAS Number | 38748-32-2 |
|---|---|
| SMILES | CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C |
| InChIKey | DFBIRQPKNDILPW-UHFFFAOYSA-N |
Product Overview
雷公藤内酯 (CAS 38748-32-2), with molecular formula C20H24O6 and molecular weight 360.16 g/mol. IUPAC: 8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one.
Chemical Property Profile of 雷公藤内酯
Property Insights of 雷公藤内酯
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 雷公藤内酯. The TPSA of 84.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 雷公藤内酯. Following Lipinski's Rule of Five, 雷公藤内酯 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 雷公藤内酯?
The CAS number of 雷公藤内酯 is 38748-32-2.
What is the molecular formula of 雷公藤内酯?
The molecular formula of 雷公藤内酯 is C20H24O6.
What is the molecular weight of 雷公藤内酯?
The molecular weight of 雷公藤内酯 is 360.16 g/mol.
Where can I buy 雷公藤内酯?
You can request a quote for 雷公藤内酯 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 雷公藤内酯?
Yes, KEHONG BIO provides custom synthesis services for 雷公藤内酯 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.