磷酸氢化可的松
TL;DR: 磷酸氢化可的松 (CAS 3863-59-0) is a chemical compound with molecular formula C21H31O8P and molecular weight 442.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
磷酸氢化可的松
[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] dihydrogen phosphate
Also Known As: Corphos, Hydrocortisone phosphate, Cortisol phosphate, Cortisol 21-phosphate, Cortisol, phosphate (salt)
| Molecular Formula | C21H31O8P |
|---|---|
| Molecular Weight | 442.18 g/mol |
| LogP | 0.0 |
| Topological Polar Surface Area | 141.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 442.17566 |
| Heavy Atoms | 30 |
| Complexity | 848.0 |
Chemical Identifiers
| CAS Number | 3863-59-0 |
|---|---|
| SMILES | CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)COP(=O)(O)O)O)C)O |
| InChIKey | BGSOJVFOEQLVMH-UHFFFAOYSA-N |
Product Overview
磷酸氢化可的松 (CAS 3863-59-0), with molecular formula C21H31O8P and molecular weight 442.18 g/mol. IUPAC: [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] dihydrogen phosphate.
Chemical Property Profile of 磷酸氢化可的松
Property Insights of 磷酸氢化可的松
The XLogP value of 0.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 磷酸氢化可的松. The TPSA of 141.0 Ų indicates high polarity, suggesting 磷酸氢化可的松 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Corphos has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Corphos?
The CAS number of Corphos is 3863-59-0.
What is the molecular formula of Corphos?
The molecular formula of Corphos is C21H31O8P.
What is the molecular weight of Corphos?
The molecular weight of Corphos is 442.18 g/mol.
Where can I buy Corphos?
You can request a quote for Corphos directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Corphos?
Yes, KEHONG BIO provides custom synthesis services for Corphos and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.