格拉非宁
TL;DR: 格拉非宁 (CAS 3820-67-5) is a chemical compound with molecular formula C19H17ClN2O4 and molecular weight 372.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
格拉非宁
2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate
Also Known As: glafenine, Glafenin, Glaphenine, Glaphenin, Glicafan
| Molecular Formula | C19H17ClN2O4 |
|---|---|
| Molecular Weight | 372.09 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 91.7 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 372.08768 |
| Heavy Atoms | 26 |
| Complexity | 467.0 |
| Melting Point | 165 |
Chemical Identifiers
| CAS Number | 3820-67-5 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C(=O)OCC(CO)O)NC2=C3C=CC(=CC3=NC=C2)Cl |
| InChIKey | GWOFUCIGLDBNKM-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
格拉非宁 (CAS 3820-67-5), with molecular formula C19H17ClN2O4 and molecular weight 372.09 g/mol. IUPAC: 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate.
Chemical Property Profile of 格拉非宁
Property Insights of 格拉非宁
The XLogP value of 3.5 indicates that Glafenine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 91.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 格拉非宁. Following Lipinski's Rule of Five, Glafenine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Glafenine?
The CAS number of Glafenine is 3820-67-5.
What is the molecular formula of Glafenine?
The molecular formula of Glafenine is C19H17ClN2O4.
What is the molecular weight of Glafenine?
The molecular weight of Glafenine is 372.09 g/mol.
Where can I buy Glafenine?
You can request a quote for Glafenine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Glafenine?
Yes, KEHONG BIO provides custom synthesis services for Glafenine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.