噻洛芬酸
TL;DR: 噻洛芬酸 (CAS 33005-95-7) is a chemical compound with molecular formula C14H12O3S and molecular weight 260.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
噻洛芬酸
2-(5-benzoylthiophen-2-yl)propanoic acid
Also Known As: tiaprofenic acid, Surgam, Tiaprofensaeure, tiaprofen, Acido tiaprofenico
| Molecular Formula | C14H12O3S |
|---|---|
| Molecular Weight | 260.05 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 82.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 260.05072 |
| Heavy Atoms | 18 |
| Complexity | 323.0 |
| Melting Point | 96 |
| Solubility | 3.24e-02 g/L |
Chemical Identifiers
| CAS Number | 33005-95-7 |
|---|---|
| SMILES | CC(C1=CC=C(S1)C(=O)C2=CC=CC=C2)C(=O)O |
| InChIKey | GUHPRPJDBZHYCJ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 17 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
噻洛芬酸 (CAS 33005-95-7), with molecular formula C14H12O3S and molecular weight 260.05 g/mol. IUPAC: 2-(5-benzoylthiophen-2-yl)propanoic acid.
Chemical Property Profile of 噻洛芬酸
Property Insights of 噻洛芬酸
The XLogP value of 3.3 indicates that 噻洛芬酸 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 82.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 噻洛芬酸. Following Lipinski's Rule of Five, 噻洛芬酸 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 噻洛芬酸?
The CAS number of 噻洛芬酸 is 33005-95-7.
What is the molecular formula of 噻洛芬酸?
The molecular formula of 噻洛芬酸 is C14H12O3S.
What is the molecular weight of 噻洛芬酸?
The molecular weight of 噻洛芬酸 is 260.05 g/mol.
Where can I buy 噻洛芬酸?
You can request a quote for 噻洛芬酸 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 噻洛芬酸?
Yes, KEHONG BIO provides custom synthesis services for 噻洛芬酸 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.