Thioproperazine
TL;DR: Thioproperazine (CAS 316-81-4) is a chemical compound with molecular formula C22H30N4O2S2 and molecular weight 446.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide
Also Known As: Thioproperazine, Thioperazine, Thioproperazin, Sulfenazin, Vontil
| Molecular Formula | C22H30N4O2S2 |
|---|---|
| Molecular Weight | 446.18 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 80.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 446.18103 |
| Heavy Atoms | 30 |
| Complexity | 661.0 |
| Melting Point | 140 |
| Solubility | 5.69e-02 g/L |
Chemical Identifiers
| CAS Number | 316-81-4 |
|---|---|
| SMILES | CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)N(C)C |
| InChIKey | VZYCZNZBPPHOFY-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Thioproperazine (CAS 316-81-4), with molecular formula C22H30N4O2S2 and molecular weight 446.18 g/mol. IUPAC: N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide.
Chemical Property Profile of Thioproperazine
Property Insights of Thioproperazine
The XLogP value of 3.7 indicates that Thioproperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Thioproperazine. Following Lipinski's Rule of Five, Thioproperazine has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thioproperazine?
The CAS number of Thioproperazine is 316-81-4.
What is the molecular formula of Thioproperazine?
The molecular formula of Thioproperazine is C22H30N4O2S2.
What is the molecular weight of Thioproperazine?
The molecular weight of Thioproperazine is 446.18 g/mol.
Where can I buy Thioproperazine?
You can request a quote for Thioproperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thioproperazine?
Yes, KEHONG BIO provides custom synthesis services for Thioproperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.