![1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea structure](/static/products/3031/303147-93-5.webp)
1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea
TL;DR: 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea (CAS 303147-93-5) is a chemical compound with molecular formula C18H13ClF4N4O2S and molecular weight 460.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-3-[3-[(4-fluorophenyl)methoxy]thiophen-2-yl]urea
Also Known As: 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea, 11F-022, 1-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]-3-[3-[(4-fluorophenyl)methoxy]thiophen-2-yl]urea, 2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-{3-[(4-fluorobenzyl)oxy]-2-thienyl}-1-hydrazinecarboxamide, 2-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-N-(3-[(4-FLUOROBENZYL)OXY]-2-THIENYL)-1-HYDRAZINECARBOXAMIDE
| Molecular Formula | C18H13ClF4N4O2S |
|---|---|
| Molecular Weight | 460.04 g/mol |
| LogP | 5.682 |
| Topological Polar Surface Area | 75.28 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 460.0384 |
| Heavy Atoms | 30 |
| Complexity | 1027.771 |
Chemical Identifiers
| CAS Number | 303147-93-5 |
|---|---|
| SMILES | C1=CC(=CC=C1COC2=C(SC=C2)NC(=O)NNC3=C(C=C(C=N3)C(F)(F)F)Cl)F |
Product Overview
1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea (CAS 303147-93-5), with molecular formula C18H13ClF4N4O2S and molecular weight 460.04 g/mol. IUPAC: 1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-3-[3-[(4-fluorophenyl)methoxy]thiophen-2-yl]urea.
Chemical Property Profile of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea
Property Insights of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea
The XLogP value of 5.682 indicates that 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.28 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea. Following Lipinski's Rule of Five, 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea?
The CAS number of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea is 303147-93-5.
What is the molecular formula of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea?
The molecular formula of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea is C18H13ClF4N4O2S.
What is the molecular weight of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea?
The molecular weight of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea is 460.04 g/mol.
Where can I buy 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea?
You can request a quote for 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea?
Yes, KEHONG BIO provides custom synthesis services for 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-{3-[(4-fluorophenyl)methoxy]thiophen-2-yl}urea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.