N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide
TL;DR: N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide (CAS 303103-99-3) is a chemical compound with molecular formula C15H10BrFN4OS and molecular weight 391.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(5-bromo-2-fluorophenyl)methylideneamino]-5-thiophen-2-yl-1H-pyrazole-3-carboxamide
Also Known As: N'-(5-Bromo-2-fluorobenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide, N'-(5-BROMO-2-FLUOROBENZYLIDENE)-3-(2-THIENYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE, N-[(E)-(5-bromo-2-fluorophenyl)methylideneamino]-5-thiophen-2-yl-1H-pyrazole-3-carboxamide, 652-449-2, N'-[(E)-(5-BROMO-2-FLUOROPHENYL)METHYLIDENE]-3-(THIOPHEN-2-YL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE
| Molecular Formula | C15H10BrFN4OS |
|---|---|
| Molecular Weight | 391.97 g/mol |
| LogP | 3.8037 |
| Topological Polar Surface Area | 70.14 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 391.97427 |
| Heavy Atoms | 23 |
| Complexity | 860.25134 |
Chemical Identifiers
| CAS Number | 303103-99-3 |
|---|---|
| SMILES | C1=CSC(=C1)C2=CC(=NN2)C(=O)N/N=C/C3=C(C=CC(=C3)Br)F |
Product Overview
N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide (CAS 303103-99-3), with molecular formula C15H10BrFN4OS and molecular weight 391.97 g/mol. IUPAC: N-[(E)-(5-bromo-2-fluorophenyl)methylideneamino]-5-thiophen-2-yl-1H-pyrazole-3-carboxamide.
Chemical Property Profile of N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide
Property Insights of N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide
The XLogP value of 3.8037 indicates that N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.14 Ų falls within the moderate polarity range, balancing permeability and solubility for N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide. Following Lipinski's Rule of Five, N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide?
The CAS number of N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide is 303103-99-3.
What is the molecular formula of N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide?
The molecular formula of N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide is C15H10BrFN4OS.
What is the molecular weight of N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide?
The molecular weight of N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide is 391.97 g/mol.
Where can I buy N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide?
You can request a quote for N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for N'-(5-Bromo-2-fluorobenzylidene)-3-(2-thienyl)-1H-pyrazole-5-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.