3'-叠氮-2',3'-双脱氧胸苷一磷酸
TL;DR: 3'-叠氮-2',3'-双脱氧胸苷一磷酸 (CAS 29706-85-2) is a chemical compound with molecular formula C10H14N5O7P and molecular weight 347.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3'-叠氮-2',3'-双脱氧胸苷一磷酸
[3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
Also Known As: AzddTMP, Zidovudine monophosphate, Zidovudine 5'-monophosphate, [3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate, [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
| Molecular Formula | C10H14N5O7P |
|---|---|
| Molecular Weight | 347.06 g/mol |
| LogP | -1.0 |
| Topological Polar Surface Area | 140.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Exact Mass | 347.06308 |
| Heavy Atoms | 23 |
| Complexity | 640.0 |
Chemical Identifiers
| CAS Number | 29706-85-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)O)N=[N+]=[N-] |
| InChIKey | OIFWQOKDSPDILA-UHFFFAOYSA-N |
Product Overview
3'-叠氮-2',3'-双脱氧胸苷一磷酸 (CAS 29706-85-2), with molecular formula C10H14N5O7P and molecular weight 347.06 g/mol. IUPAC: [3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate.
Chemical Property Profile of 3'-叠氮-2',3'-双脱氧胸苷一磷酸
Property Insights of 3'-叠氮-2',3'-双脱氧胸苷一磷酸
The XLogP value of -1.0 indicates that 3'-叠氮-2',3'-双脱氧胸苷一磷酸 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 140.0 Ų indicates high polarity, suggesting 3'-叠氮-2',3'-双脱氧胸苷一磷酸 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 3'-叠氮-2',3'-双脱氧胸苷一磷酸 has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-叠氮-2',3'-双脱氧胸苷一磷酸?
The CAS number of 3'-叠氮-2',3'-双脱氧胸苷一磷酸 is 29706-85-2.
What is the molecular formula of 3'-叠氮-2',3'-双脱氧胸苷一磷酸?
The molecular formula of 3'-叠氮-2',3'-双脱氧胸苷一磷酸 is C10H14N5O7P.
What is the molecular weight of 3'-叠氮-2',3'-双脱氧胸苷一磷酸?
The molecular weight of 3'-叠氮-2',3'-双脱氧胸苷一磷酸 is 347.06 g/mol.
Where can I buy 3'-叠氮-2',3'-双脱氧胸苷一磷酸?
You can request a quote for 3'-叠氮-2',3'-双脱氧胸苷一磷酸 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-叠氮-2',3'-双脱氧胸苷一磷酸?
Yes, KEHONG BIO provides custom synthesis services for 3'-叠氮-2',3'-双脱氧胸苷一磷酸 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.