A0443/0020444
TL;DR: A0443/0020444 (CAS 296798-85-1) is a chemical compound with molecular formula C25H23F2N3O and molecular weight 419.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8E)-2-amino-4-(2-fluorophenyl)-8-[(2-fluorophenyl)methylidene]-6-propan-2-yl-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
Also Known As: A0443/0020444, (8E)-2-amino-8-(2-fluorobenzylidene)-4-(2-fluorophenyl)-6-(propan-2-yl)-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile, (8E)-2-AMINO-4-(2-FLUOROPHENYL)-8-[(2-FLUOROPHENYL)METHYLIDENE]-6-(PROPAN-2-YL)-4H,5H,6H,7H,8H-PYRANO[3,2-C]PYRIDINE-3-CARBONITRILE, (8E)-2-amino-4-(2-fluorophenyl)-8-[(2-fluorophenyl)methylidene]-6-propan-2-yl-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile, (E)-2-amino-8-(2-fluorobenzylidene)-4-(2-fluorophenyl)-6-isopropyl-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
| Molecular Formula | C25H23F2N3O |
|---|---|
| Molecular Weight | 419.18 g/mol |
| LogP | 4.83418 |
| Topological Polar Surface Area | 62.28 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 419.1809 |
| Heavy Atoms | 31 |
| Complexity | 1157.3522 |
Chemical Identifiers
| CAS Number | 296798-85-1 |
|---|---|
| SMILES | CC(C)N1C/C(=C\C2=CC=CC=C2F)/C3=C(C1)C(C(=C(O3)N)C#N)C4=CC=CC=C4F |
Product Overview
A0443/0020444 (CAS 296798-85-1), with molecular formula C25H23F2N3O and molecular weight 419.18 g/mol. IUPAC: (8E)-2-amino-4-(2-fluorophenyl)-8-[(2-fluorophenyl)methylidene]-6-propan-2-yl-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile.
Chemical Property Profile of A0443/0020444
Property Insights of A0443/0020444
The XLogP value of 4.83418 indicates that A0443/0020444 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.28 Ų falls within the moderate polarity range, balancing permeability and solubility for A0443/0020444. Following Lipinski's Rule of Five, A0443/0020444 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of A0443/0020444?
The CAS number of A0443/0020444 is 296798-85-1.
What is the molecular formula of A0443/0020444?
The molecular formula of A0443/0020444 is C25H23F2N3O.
What is the molecular weight of A0443/0020444?
The molecular weight of A0443/0020444 is 419.18 g/mol.
Where can I buy A0443/0020444?
You can request a quote for A0443/0020444 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for A0443/0020444?
Yes, KEHONG BIO provides custom synthesis services for A0443/0020444 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.