格列吡嗪
TL;DR: 格列吡嗪 (CAS 29094-61-9) is a chemical compound with molecular formula C21H27N5O4S and molecular weight 445.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
格列吡嗪
N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide
Also Known As: glipizide, Glucotrol, Glydiazinamide, Glibenese, Melizide
| Molecular Formula | C21H27N5O4S |
|---|---|
| Molecular Weight | 445.18 g/mol |
| LogP | 1.9 |
| Topological Polar Surface Area | 139.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 445.17838 |
| Heavy Atoms | 31 |
| Complexity | 697.0 |
| Melting Point | 200-203 |
| Solubility | 37.2 |
Chemical Identifiers
| CAS Number | 29094-61-9 |
|---|---|
| SMILES | CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3 |
| InChIKey | ZJJXGWJIGJFDTL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 16 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
格列吡嗪 (CAS 29094-61-9), with molecular formula C21H27N5O4S and molecular weight 445.18 g/mol. IUPAC: N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide.
Chemical Property Profile of 格列吡嗪
Property Insights of 格列吡嗪
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 格列吡嗪. The TPSA of 139.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 格列吡嗪. Following Lipinski's Rule of Five, 格列吡嗪 has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 格列吡嗪?
The CAS number of 格列吡嗪 is 29094-61-9.
What is the molecular formula of 格列吡嗪?
The molecular formula of 格列吡嗪 is C21H27N5O4S.
What is the molecular weight of 格列吡嗪?
The molecular weight of 格列吡嗪 is 445.18 g/mol.
Where can I buy 格列吡嗪?
You can request a quote for 格列吡嗪 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 格列吡嗪?
Yes, KEHONG BIO provides custom synthesis services for 格列吡嗪 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.