阿佐塞米
TL;DR: 阿佐塞米 (CAS 27589-33-9) is a chemical compound with molecular formula C12H11ClN6O2S2 and molecular weight 370.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
阿佐塞米
2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide
Also Known As: azosemide, Azosemid, Diart, Azosemida, Azosemidum
| Molecular Formula | C12H11ClN6O2S2 |
|---|---|
| Molecular Weight | 370.01 g/mol |
| LogP | 1.5 |
| Topological Polar Surface Area | 163.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 370.00735 |
| Heavy Atoms | 23 |
| Complexity | 504.0 |
| Melting Point | 219.5 °C |
Chemical Identifiers
| CAS Number | 27589-33-9 |
|---|---|
| SMILES | C1=CSC(=C1)CNC2=CC(=C(C=C2C3=NNN=N3)S(=O)(=O)N)Cl |
| InChIKey | HMEDEBAJARCKCT-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
阿佐塞米 (CAS 27589-33-9), with molecular formula C12H11ClN6O2S2 and molecular weight 370.01 g/mol. IUPAC: 2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide.
Chemical Property Profile of 阿佐塞米
Property Insights of 阿佐塞米
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 阿佐塞米. The TPSA of 163.0 Ų indicates high polarity, suggesting 阿佐塞米 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 阿佐塞米 has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 阿佐塞米?
The CAS number of 阿佐塞米 is 27589-33-9.
What is the molecular formula of 阿佐塞米?
The molecular formula of 阿佐塞米 is C12H11ClN6O2S2.
What is the molecular weight of 阿佐塞米?
The molecular weight of 阿佐塞米 is 370.01 g/mol.
Where can I buy 阿佐塞米?
You can request a quote for 阿佐塞米 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 阿佐塞米?
Yes, KEHONG BIO provides custom synthesis services for 阿佐塞米 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.