洛非帕明
TL;DR: 洛非帕明 (CAS 23047-25-8) is a chemical compound with molecular formula C26H27ClN2O and molecular weight 418.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
洛非帕明
1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone
Also Known As: LOFEPRAMINE, Lopramine, Amplit, Lofepramina, Lofepraminum
| Molecular Formula | C26H27ClN2O |
|---|---|
| Molecular Weight | 418.18 g/mol |
| LogP | 6.8 |
| Topological Polar Surface Area | 23.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 418.18118 |
| Heavy Atoms | 30 |
| Complexity | 523.0 |
| Melting Point | 104-406 °C |
| Solubility | In water, 1.4X10-2 mg/L @ 25 °C /Estimated/ |
| Vapor Pressure | 1.5X10-9 mm Hg @ 25 °C /Estimated/ |
Chemical Identifiers
| CAS Number | 23047-25-8 |
|---|---|
| SMILES | CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl |
| InChIKey | SAPNXPWPAUFAJU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
洛非帕明 (CAS 23047-25-8), with molecular formula C26H27ClN2O and molecular weight 418.18 g/mol. IUPAC: 1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone.
Chemical Property Profile of 洛非帕明
Property Insights of 洛非帕明
The XLogP value of 6.8 indicates that 洛非帕明 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.6 Ų, 洛非帕明 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 洛非帕明 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 洛非帕明?
The CAS number of 洛非帕明 is 23047-25-8.
What is the molecular formula of 洛非帕明?
The molecular formula of 洛非帕明 is C26H27ClN2O.
What is the molecular weight of 洛非帕明?
The molecular weight of 洛非帕明 is 418.18 g/mol.
Where can I buy 洛非帕明?
You can request a quote for 洛非帕明 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 洛非帕明?
Yes, KEHONG BIO provides custom synthesis services for 洛非帕明 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.