2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid
TL;DR: 2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid (CAS 220955-03-3) is a chemical compound with molecular formula C14H12N4O and molecular weight 252.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid
2-(2-hydroxyphenyl)-3H-benzimidazole-5-carboximidamide
Also Known As: 1ghw, 1gi1, 1gi4, 1gi8, 1o2s
| Molecular Formula | C14H12N4O |
|---|---|
| Molecular Weight | 252.10 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 98.8 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 252.1011 |
| Heavy Atoms | 19 |
| Complexity | 348.0 |
Chemical Identifiers
| CAS Number | 220955-03-3 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C2=NC3=C(N2)C=C(C=C3)C(=N)N)O |
| InChIKey | URJKRCBBKTXOHS-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid (CAS 220955-03-3), with molecular formula C14H12N4O and molecular weight 252.10 g/mol. IUPAC: 2-(2-hydroxyphenyl)-3H-benzimidazole-5-carboximidamide.
Chemical Property Profile of 2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid
Property Insights of 2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid. The TPSA of 98.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxylic acid. Following Lipinski's Rule of Five, 1ghw has 4 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1ghw?
The CAS number of 1ghw is 220955-03-3.
What is the molecular formula of 1ghw?
The molecular formula of 1ghw is C14H12N4O.
What is the molecular weight of 1ghw?
The molecular weight of 1ghw is 252.10 g/mol.
Where can I buy 1ghw?
You can request a quote for 1ghw directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1ghw?
Yes, KEHONG BIO provides custom synthesis services for 1ghw and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.