![3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 structure](/static/products/2207/220749-41-7.webp)
3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮
TL;DR: 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 (CAS 220749-41-7) is a chemical compound with molecular formula C17H11ClN2O and molecular weight 294.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮
3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
Also Known As: cdk1 inhibitor, cmpd 8a, CDK1 inhibitor 8a, CDK1-IN-2, 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
| Molecular Formula | C17H11ClN2O |
|---|---|
| Molecular Weight | 294.06 g/mol |
| LogP | 4.0 |
| Topological Polar Surface Area | 44.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 294.056 |
| Heavy Atoms | 21 |
| Complexity | 464.0 |
Chemical Identifiers
| CAS Number | 220749-41-7 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CC3=C(NC4=CC=CC=C43)Cl)C(=O)N2 |
| InChIKey | QJKBRWSJWQVKLY-UHFFFAOYSA-N |
Product Overview
3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 (CAS 220749-41-7), with molecular formula C17H11ClN2O and molecular weight 294.06 g/mol. IUPAC: 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one.
Chemical Property Profile of 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮
Property Insights of 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮
The XLogP value of 4.0 indicates that 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.9 Ų, 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮?
The CAS number of 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 is 220749-41-7.
What is the molecular formula of 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮?
The molecular formula of 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 is C17H11ClN2O.
What is the molecular weight of 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮?
The molecular weight of 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 is 294.06 g/mol.
Where can I buy 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮?
You can request a quote for 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮?
Yes, KEHONG BIO provides custom synthesis services for 3-[(2-氯-1H-吲哚-3-基)亚甲基]-1H-吲哚-2-酮 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.